What's new in bioscience: research, preprints, clinical trials, funding and company moves. Global, with an India filter. Nothing here is hand-picked. The site collects and sorts itself, every day.
Updated · 160 items
Peer-reviewed papers. Global items come only from a whitelist of 46 core journals. A new paper has no citations yet, so where it published is the only quality signal available on the day it appears. India-affiliated work uses a wider net, because the local ecosystem mostly does not publish in Nature.
BACKGROUND: Left ventricular (LV) hypertrabeculation, formerly termed LV noncompaction, is a heterogeneous myocardial entity linked to adverse cardiovascular outcomes. This study evaluated embolic risk in patients with dilated cardiomyopathy (DCM) according to…
<title>Abstract</title> Crop yield prediction plays a very important role in productivity growth. Prediction of the crop yield in particular area helps the farmer to choose the right crop to be grown in the land. With crop yield prediction crop recommendation…
The rapid emergence and dissemination of antimicrobial resistance (AMR) among bacterial pathogens, particularly the ESKAPE group (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and…
Cardiovascular diseases (CVDs) remain the foremost cause of death globally, responsible for 19.2 million deaths and 437 million disability-adjusted life years in 2023, with prevalent cases having more than doubled since 1990. No approved therapy restores…
Background: Ginger (Zingiber officinale) is a medicinally important spice rich in bioactive compounds, particularly 6-gingerol, which contributes to its characteristic pungency. These compounds exhibit diverse pharmacological activities, including anticancer,…
Purpose The research examines consumer resistance towards genetically modified (GM) foods, using innovation resistance theory (IRT) as the theoretical framework and religiosity as a moderating influence. Design/methodology/approach A cross-sectional survey of…
Purpose This article illustrates how the Everyday Entry Pathway of Everyday Practice-based Research (EPBR-E) can support movement from a recurring concern in everyday work towards epistemic and practical clarity. Using food waste in residential aged care as an…
Flemingia stricta, a medicinal herb traditionally used by Indian tribal communities belonging to the Fabaceae family, is widely used for treating inflammation, rheumatism, bone fractures and respiratory disorders. The plant is also reported to possess…
PURPOSE: To determine the prevalence of visual field (VF) defect among Indian driving licence (DL) holders and to evaluate their eligibility according to UK Driver and Vehicle Licensing Agency (DVLA) visual fitness standards. METHOD: Design: This…
Objective: To determine the incidence of and factors associated with magnetic resonance imaging (MRI)-detected postoperative spinal epidural hematoma after single-level unilateral biportal endoscopic (UBE) lumbar decompression with or without discectomy, and…
Tuberculosis of the craniovertebral junction (CVJ) is an uncommon condition, particularly in the pediatric population, and may present with severe neurological deficits due to instability and spinal cord compression. Surgical management is especially…
PURPOSE: To compare the demographic, clinical, visual, and structural parameters in idiopathic intracranial hypertension (IIH) patients with and without anemia. METHODS: This was a prospective comparative clinical study conducted at a tertiary eye care center.…
ABSTRACT Cardio-cerebral infarction syndrome (CCIS) represents a rare but clinically challenging overlap of acute ischemic stroke (AIS) and acute myocardial infarction (AMI), where competing priorities of reperfusion create therapeutic dilemmas. We report a…
Background: Chronic kidney disease (CKD) is a major public health problem associated with substantial morbidity and mortality. While diabetes mellitus and hypertension remain the leading causes of CKD, increasing attention is being directed toward chronic…
Importance: Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C-related burden is critical for guiding prevention and treatment…
Abstract Brain computation depends on intricately connected yet highly distributed neural networks. Owing to the absence of the requisite technologies, causally testing fundamental hypotheses on inter-areal processing has remained largely out of reach. Here,…
The differentiation of human pluripotent stem cells to kidney requires the accurate recapitulation of complex morphogenetic patterning events within an in vitro environment. Current protocols are assumed to accurately pattern through intermediate mesoderm to…
Abstract Clinical sleep studies capture multiple physiologic signals, yet interpretation is often reduced to single summary measures of limited prognostic value, such as the apnea–hypopnea index. We present a foundation model that learns rich representations…
Inflammasomes are high-molecular-weight complexes that play integral roles in the innate immune system, triggering an inflammatory cascade to protect against cellular stresses such as pathogenic bacteria. Both canonical and non-canonical inflammasomes have…
The Hawaiian honeycreepers, one of the world’s most iconic adaptive radiations, are facing a human-mediated extinction crisis. More than 60 Hawaiian honeycreepers (Fringillidae: Carduelinae: Drepanidini) evolved from a single rosefinch-like ancestor that…
Adoptive cell transfer of tumor infiltrating CD4 + T cells or T cells genetically modified to express antitumor CD4 + T cell receptors (TCRs) has shown clinical efficacy in patients with advanced solid tumors. We previously defined unique transcriptomic states…
Liver cancer is the fourth leading cause of global cancer mortality, with hepatocellular carcinoma (HCC) accounting for most primary liver cancers. The nucleolus, as the primary site of ribosome biogenesis, plays a crucial role in HCC development. Here, we…
T/B cell receptors (T/BCR), coordinating antigen-targeting immune response, play crucial roles in anti-tumor immune response. Tracking T and B cell clonal evolution in situ at single-cell resolution is essential for understanding the adaptive immune responses.…
Abnormal activation of fibroblast growth factor receptor 2 (FGFR2) drives tumorigenesis in various cancers. Clinical use of pan-FGFR inhibitors is limited due to emerging acquired resistance mutations within the FGFR2 kinase domain and adverse effects…
Importance Hodgkin lymphoma (HL) is a lymphoid malignancy derived from B cells. Globally, there were 82 409 new cases of HL in 2022, associated with 22 701 deaths. In the US, 8720 incident cases of HL and 1150 deaths due to HL were reported in 2025. Classic HL…
Abstract Synthetic riboswitches provide protein-independent, modular control of gene expression, yet selecting aptamers that reliably couple ligand binding to regulatory switching remains challenging. Here, we identify and mechanistically characterise G12, a…
The mammalian auditory sensory epithelium consists of hair cells (HCs), whose stereociliary bundles convert sound-evoked vibrations into electrical signals, and supporting cells (SCs), which provide mechanical stability. The transcription factor SIX1 is…
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bioRxiv and medRxiv, where new biology often lands months before the journal version. Not peer reviewed. Filtered on subject relevance rather than quality, since no quality signal exists at this stage.
BACKGROUND: Myofascial Pain Syndrome (MPS) is a common musculoskeletal pain condition associated with myofascial trigger points that has been reported to occur in 30-93% of patients who present with musculoskeletal pain. The current pharmacologic treatments…
Background: Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among individuals with diabetes, where risk remains elevated even with good glycemic control. Cardiac biomarkers such as N-terminal pro-B-type natriuretic peptide…
This formative phase of the qualitative study explored elders needs, priorities, daily routines and community resources, alongside frontline healthcare workers perspectives on delivering healthy ageing interventions in rural Maharashtra, India. Ten focus group…
Functional hyperconnectivity and hypoconnectivity in autism spectrum disorder (ASD) are typically treated as opposing expressions of a single circuit-level disturbance, but their molecular and hierarchical basis remains unclear. We combined resting-state fMRI…
BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease influenced by genetic and environmental factors, including diet. We examined the associations of dietary inflammatory potential, dietary diversity, and micronutrient adequacy with RA and…
Nitric oxide metabolism-based protein post-translational modifications, such as reversible S- nitrosylation, have been at the pinnacle of plant redox research owing to their significant correlation with seed dormancy, interaction with other signaling…
Despite its essential role in growth, the impact of sulfur limitation on mycobacterial physiology and antibiotic responsiveness remains poorly understood. Here, we combined chemical-genetic perturbations and infection models to investigate the consequences of…
As one of the strongest selective forces, predation risk induces antipredator responses in prey that not only maximise survival probability but are energetically expensive. While these responses are known to affect foraging patterns and diet composition, the…
Diverse vacuolar architectures present unique signaling challenges for intracellular bacteria, yet whether distinct niches share host requirements remains unclear. Because host kinases coordinate these complex cellular responses, we performed a comparative…
Osteoarthritis (OA) is increasingly recognized as a whole-joint disease, yet eQTL studies have focused almost exclusively on cartilage. Here we build cell-type-resolved gene regulatory maps of human synovium and infrapatellar fat pad (IPFP), integrating…
The third ventricle is a high-value site for neuromodulation due to its proximity to deep-brain targets, including the subthalamic nucleus (STN) and globus pallidus internus (GPi). This study defines the anatomical pathway via direct and medical imaging…
Neuroticism, a personality trait characterized by the predisposition to experience intense and frequent negative emotions, has been associated with an increased risk of Alzheimer's disease (AD). However, the mechanisms underlying this association remain…
Background Cardiometabolic disease is heterogeneous and incompletely resolved by conventional classification. We aimed to use expanded variables to identify data-driven phenogroups and characterise their echocardiographic and proteomic features. Methods Latent…
Background: In prospective cohort studies, where an exposure is collected repeatedly, interest often lies in determining whether the timing of that exposure has a differential effect on a later outcome. The Structured Life Course Modeling Approach (SLCMA),…
Clinical trials are fundamental to the production of medical evidence and determine who gains access to experimental therapies. Although prior work has long documented inequalities in global clinical trial participation, a systematic quantification of the…
Photoplethysmography (PPG, optical measurement of cardiac blood volume changes) is the foundation of wearable cardiac monitoring, but systematically fails on dark skin due to melanin absorption. We present the Melanin Absorption Invariance (MAI) framework: a…
Neurodegenerative diseases such as Mild Cognitive Impairment (MCI), Multiple Sclerosis (MS), Parkinson s Disease (PD), and Amyotrophic Lateral Sclerosis (ALS) are becoming more prevalent. Each of these diseases, despite its specific pathophysiological…
BackgroundPreeclampsia is a leading cause of maternal morbidity and mortality in sub-Saharan Africa (SSA). Lead exposure remains widespread, yet its contribution to preeclampsia risk has not been quantified at the population level. In 2023, SSA accounted for…
ABSTRACT Patient movements within and between hospitals create networks that can facilitate the spread of nosocomial infections. Many relevant pathogens have long-lasting carriage, allowing colonised patients to move through multiple wards across successive…
Cancer imposes a rising and largely out-of-pocket-financed burden in Nepal, yet patient-level data on how anticancer drugs are prescribed and what chemotherapy actually costs patients remain limited. This study described the drug utilization pattern and cost…
The cerebral cortex computes through a laminar microcircuit in which superficial layers integrate cortico-cortical input and deep layers issue corticospinal output. How focal injury disrupts this input-output architecture has been characterized in animal…
BackgroundPatients with hypertension commonly exhibit reduced exercise capacity. Impedance cardiography (ICG) enables continuous, non-invasive assessment of exercise-derived hemodynamic parameters; however, the relative associations of different ICG-derived…
Introduction: Mitochondrial DNA (mtDNA) is not routinely analyzed in inherited kidney disease. We evaluated mtDNA variation in families who remained genetically unresolved despite extensive testing. Methods: We reviewed pedigrees from the Wake Forest-Charles…
Whole blood offers a non-invasive window into organ health, yet it remains unclear which organ pathologies leave a detectable trace in the blood transcriptome, and whether such traces are causal or reactive. Progress has been limited because paired whole-blood…
Background: Healthcare contributes 5% of global carbon emissions, with academic and industry-sponsored clinical trials forming a meaningful share. Existing trial emission frameworks inadequately capture data storage and analysis emissions, leaving their…
Background: Critical illness is a major contributor to morbidity and mortality in low-resource settings, yet data on its prevalence, location, management, and contextual barriers to care outside intensive care units remain limited in Ethiopia. This study aimed…
Background: Psychosocial stress is a key risk factor for coronary heart disease (CHD), particularly in postmenopausal women who face both a high stress burden and elevated cardiovascular risk. DNA methylation (DNAm), a critical epigenetic modification bridging…
Background: Alcohol consumption is a modifiable risk factor linked to anxiety and depression, yet the population-level impact of reducing alcohol use on the prevalence of anxiety and depression symptoms remains unclear. Prior studies are limited by…
Background: Functional dyspepsia (FD) is among the most common gastrointestinal disorders worldwide and is characterized by symptoms including epigastric pain, early satiety, postprandial fullness, bloating, and upper abdominal discomfort. Itopride…
Abstract Background Despite widespread recognition of the value of lived experience (LE) involvement in healthcare research and increased LE involvement activity, we lack established implementation methods and instruments for reporting and evaluating impact.…
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Phase 2 and 3 interventional studies from ClinicalTrials.gov. One real limit worth knowing: Indian trials mostly register with CTRI, not CT.gov. So "India" here means a global study running Indian sites, which is where large pharma touches India. Reading CTRI is the next thing to add.
This study will look at the long-term effects of semaglutide (active medicine) on diabetic eye disease when compared to placebo (dummy medicine). The study will be performed in people with type 2 diabetes. Participants will either get…
Migraine is a common, heterogeneous neurological disorder affecting approximately 10-15% of the global population and is the third most prevalent disease worldwide. A wide range of pharmacological agents is available for migraine…
An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann-Pick type C disease and in…
The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron compared with placebo in adults with Type 2 Diabetes Mellitus (T2DM), treated with a background insulin and other background glucose-lowering…
This research is being conducted to asses if HT-6184 is effective in the treatment of Very Low, Low, or Intermediate Risk Myelodysplastic Syndrome (MDS) and Symptomatic Anemia. The study includes a 28-day Screening Period followed by a 16-…
This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.
This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with overweight or obesity, and obstructive sleep apnoea treated with positive airway pressure. There are 2 study treatments in this study taken as…
A global study to assess the efficacy and safety of osimertinib following chemoradiation in patients with stage III unresectable Epidermal Growth Factor Receptor Mutation Positive non-small cell lung cancer
The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron, compared with placebo in adults with type 2 diabetes mellitus (T2DM) and impaired renal function, who are or will be on a background of…
Semaglutide is a medicine studied in patients with NASH. Semaglutide is a well-known medicine, which is already used by doctors to treat type 2 diabetes in many countries. Participants will either get semaglutide or a dummy medicine - which…
This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease…
The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron and dapagliflozin in combination, compared with elecoglipron alone and dapagliflozin alone, in adults with type 2 diabetes mellitus (T2DM)…
A5409/RAD-TB is an adaptive Phase 2 randomized, controlled, open-label, dose-ranging, platform protocol to evaluate the safety and efficacy of multidrug regimens for the treatment of adults with drug-susceptible pulmonary tuberculosis (TB).…
This is a multicenter trial with recruitment planned at ophthalmology clinics specializing in corneal diseases in India, Brazil, and at Stanford University and Bascom Palmer Eye Institute in the United States. Fusarium keratitis is common…
An 18-month double-blind, randomized, placebo-controlled, multicenter, Phase 3 study to evaluate the safety and efficacy of oral nizubaglustat (AZ-3102) in late-infantile and juvenile forms of Niemann-Pick type C disease
This Study (AFIL-IJZ-3002) is designed to evaluate the safety, efficacy and immunogenicity of MYL-1701P among a group of participants successfully completing MYL-1701P-3001 (NCT03610646) study.
The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer…
Researchers are looking for new ways to treat metastatic cervical cancer. Cervical cancer is cancer in the cervix, the lower part of the uterus (womb). Metastatic means the cancer has spread to other parts of the body. Researchers want to…
The purpose of this study is to evaluate the clinical efficacy (GALAXI 1), clinical and endoscopic efficacy (GALAXI 2 and GALAXI 3) and safety of guselkumab in participants with Crohn's disease.
This is an adaptive prospective, multi-center, randomized, double-blind, placebo-controlled study to evaluate the safety, efficacy, pharmacokinetics, and pharmacodynamics of WAL0921 in subjects with glomerular kidney disease and…
This phase II trial studies the possible benefits of treatment with different combinations of the drugs durvalumab, olaparib and cediranib vs. the usual treatment in patients with ovarian, primary peritoneal, or fallopian tube cancer that…
Background: Focal segmental glomerulosclerosis (FSGS) is a disease that causes scarring in parts of the kidneys that filter waste. This can lead to protein loss in the urine, which can worsen kidney function. The kidneys may fail over time,…
The primary purpose of this study is to evaluate the efficacy and safety of secutrelvir in symptomatic nonhospitalized adult and adolescent participants with COVID-19 who are at high risk for progression to severe disease.
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events. GLP-1 analogues are anti-obesity medications that are cardioprotective in…
This randomized phase III trial studies chemotherapy to see how well it works with or without bevacizumab in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or that has spread to other parts of…
This trial is conducted in China. The aim is to compare BGM0504 Injection 15 mg with semaglutide 1.0 mg in Chinese T2DM patients with obesity and inadequate control despite diet and exercise. Over 52 weeks of once weekly treatment, efficacy…
This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.
This study is an open-label, single-arm, exploratory study designed to evaluate the efficacy and safety of Obinutuzumab beta combined with a rapid-tapering glucocorticoid regimen in patients with new-onset ANCA-associated glomerulonephritis…
Hidradenitis suppurativa (HS) is an inflammatory skin disease that causes painful lesions in the axilla (underarm), inguinal (groin) and anogenital (anal/genital) regions. This study will assess how safe and effective upadacitinib is in…
The purpose of this research study is to try to see whether an experimental drug, PUL 042 Inhalation Solution (PUL 042), is effective in reducing the severity of lung infections in patients with hematologic malignancies and recipients of…
This Phase 3 clinical trial is designed to evaluate the efficacy and safety of maridebart cafraglutide compared to placebo over a 52-week period in adults with obstructive sleep apnea (OSA) who are receiving positive airway pressure (PAP)…
Background: Abnormal fats in the blood can lead to many problems, including heart disease. Researchers want to learn more about how eating meals with different levels of nutrients affects fats in the blood. Specifically, they want to study…
The purpose of this study is to characterize the safety and efficacy profile of ACP-196 (acalabrutinib) in subjects with relapsed or refractory Mantle Cell Lymphoma (MCL).
This is a 1:1 randomized, open label, multi-center phase I/II trial to evaluate the safety, dosing, efficacy, and biological activity of adding IMNN-001 to chemotherapy + BEV compared to chemotherapy + BEV alone.
This phase II trial compares cabozantinib alone and the combination of cabozantinib and nivolumab to standard chemotherapy in the treatment of patients with non-squamous non-small cell lung cancer (NSCLC). Cabozantinib may stop the growth…
Background: Obesity and related illnesses cause at least 2.8 million deaths each year worldwide. Few treatments exist for obesity that are safe and widely available. A study drug (mirabegron \[MG\]) combined with a supplement (alpha-lipoic…
This study is open to adults with solid tumours who received at least 4 cycles of treatment with brigimadlin in a previous study. The goal of this study is to find out how well people with solid tumours tolerate long-term treatment with…
This study will assess the safety and tolerability of SPK-8011QQ in adult males with moderately severe to severe hemophilia A.
This phase II trial studies how well osimertinib works in treating patients with non-small cell lung cancer with EGFR exon 20 insertion mutation that is stage IIIB-IV or has come back after a period of improvement (recurrent). Osimertinib…
Sixty patients will be selected from the outpatient clinic in the Oral Medicine and Periodontology Department, Faculty of Dentistry, Mansoura University, Egypt, according to preoperative clinical and radiographic data that will be used to…
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Rounds, approvals, launches and company moves from 13 trade and business feeds. Specialist bioscience outlets pass through. General business feeds have to earn their place on a keyword in the headline.
Imports from Asean increased by 14% to nearly Rs 13,000 crore FY25-26, led by syringes, medical gloves, dialysis products, consumables and imaging equipment, including X-ray machines, making it harder for companies to…
Government has increased the budget in health research along with new schemes/initiatives to make research grants more competitive and accessible. The budgetary allocation for the Indian Council of Medical Research…
Molbio Diagnostics filed its red herring prospectus (RHP) with the Registrar of Companies on August 3, 2026. The public issue will open on August 10 and close on August 12, and the anchor book will open on August 7. The…
KKR is gaining a company that makes critical components and devices used in heart treatments, pain management therapies and other medical technologies for many of the world's leading medical device manufacturers.
Its net profit was at ₹55.50 crore in the year-ago period
IPO comprises an offer for sale by promoters and investor selling shareholder through the book-building process. The post Encube Ethicals files DRHP with SEBI for Rs 3,000 crore IPO appeared first on Express Pharma .
An anti-dumping investigation into dialyser imports from China and Malaysia has drawn fresh attention to a broader problem facing India’s medical device industry: a steady rise in low-priced imports that is squeezing…
As per the latest study conducted by the Indian Council of Medical Research (ICMR) under its i-DRONE initiative, drone-assisted transport of tuberculosis (TB) sputum samples has been found to significantly reduce the…
Doctors at King George’s Medical University (KGMU) have developed a portable, screen-free handheld device that can quickly detect internal bleeding in trauma patients. The innovation has the potential to improve…
The Maharashtra government will soon introduce a state ambulance policy aimed at making emergency medical transport more efficient and accountable, with every registered ambulance brought under real-time digital…
Krishna Institute of Medical Sciences (KIMS) reported a sharp decline in net profit for the June quarter, despite strong growth in revenue and operating profit. The hospital chain’s consolidated net profit fell 47.2%…
The disposable syringes market size is valued at USD 18.36 billion in 2026 and is projected to reach USD 24.94 billion by 2031, registering a CAGR of 6.32% during the 2026–2031 forecast period, according to Mordor…
the Government Institute of Medical Sciences (GIMS), Greater Noida, through its Centre for Medical Innovation (CMI), is set to launch the Uttar Pradesh Startup Clinic in collaboration with the MedTech Centre of…
Brazilian President Luiz Inacio Lula da Silva on Monday held discussions with Indian cardiac surgeon Dr Devi Shetty on exploring cooperation to strengthen Brazil’s public healthcare system through smart hospital…
Strong volume growth and lower input costs boosted margins in the June quarter, with the company saying it does not expect further pricing action in the near term.
Union Minister of State for Agriculture and Farmers’ Welfare Bhagirath Choudhary tells the Lok Sabha that it has affected soil physical health without appropriate management practices
The Pune-based company makes sub-20 horsepower robotic equipment for vineyards and horticulture farms, aimed at progressive farmers and shared cultivators.
The breakthrough genome resource is expected to speed gene discovery, precision breeding and productivity gains for one of India’s key pulse crops.
African Swine Fever is one of the most devastating trans-boundary animal diseases affecting domestic and wild pigs worldwide
Responding to a query in the Rajya Sabha, Nadda said public health and hospitals are state subjects and the Centre provides technical and financial support to states and Union territories under the National Health…
The new model, described in a study published in the journal Proceedings of the National Academy of Sciences, also shows how patterns of brain changes correlate with changes in cognitive function across one's lifespan,…
Prashant Nagre says the NSE listing strengthens Fermenta’s capital market presence and shareholder engagement The post Fermenta Biotech lists equity shares on NSE appeared first on Express Pharma .
Amit Agarwal explains how Howden India developed a cancer care policy for employers, while AstraZeneca India integrates it into its employee health benefits The post Howden India develops Cancer Care Group Policy;…
India's food regulator FSSAI has banned Dabur India from selling many products. These products included honey and cow ghee with misleading '100 per cent' claims. The regulator stated these claims were unverifiable and…
On Monday evening, the govt issued a GR directing MMC to begin registration of CCMP-BHMS practitioners, confirmed MMC registrar Dr Rakesh Waghmare.
Private equity giant KKR is expanding its healthcare portfolio with a deal to take medtech manufacturing giant Integer private for approximately $5.7 billion.
Latigo Biotherapeutics has fleshed out its plans for an IPO to finance the development of its clinical-stage pipeline of non-opioid pain management drugs.
Pathos AI has agreed to pay $125 million for a bispecific antibody-drug conjugate from China’s Alphamab Oncology, while adding a Big Pharma partner in the form of AstraZeneca.
Months after reports first linked Curium to a potential Lantheus takeover, the radiopharma players have made it official with a deal worth up to $8 billion.
BlossomHill Therapeutics plans to raise $111.7 million to fund the clinical journey of its potential challenger to Tagrisso.
The Fierce Biotech Fundraising Tracker records venture capital rounds of $50 million or more secured by biotechs.
Apnimed has raised $192 million for its upsized IPO, with the proceeds earmarked to fund the launch of its sleep apnea pill.
GSK is boosting its AI chops with a new deal worth up to $110 million with Relation.
CapVest Partners-backed Curium has agreed to acquire rival US-based radiopharmaceutical company Lantheus in an all-cash deal worth up to nearly $8bn.
One of the largest global pharma companies would be created if a deal were to materialise.
Moderna's imminent FDA vaccine decision, TCGX launches $400M Asia biotech fund, and more biotech news
AstraZeneca stock fell as investors balked at reports of merger talks with Bristol Myers Squibb about forming one of the world's biggest drugmakers
IMPACT Therapeutics and Pharmanovia have entered an exclusive licensing deal worth up to $488.3m, giving Pharmanovia rights to manufacture, develop, and commercialise senaparib in 66 countries.
Ratio Therapeutics, a US-based developer of radiopharmaceuticals for cancer treatment, has closed a $70m Series C financing round.
Contract research organization Icon announced a multi-year collaboration with Anthropic this week to bring Claude’s AI capabilities to clinical trials.
Amgen has ended development of its early-stage obesity drug AMG 513, foisting its hopes for a slice of the massive weight loss market onto the shoulders of phase 3 candidate MariTide.
Smith & Nephew has lowered its 2026 sales outlook after weakness in U.S. orthopedics and wound care outweighed stronger growth in sports medicine.
Who should be a 2026 Fiercest Woman in Life Sciences? Nominations are open for women making an impact across pharma, biotech, medtech and beyond. The deadline is Sept. 18.
Lisata is laying off 72% of its workforce, including its chief medical officer, as the solid tumor biotech tries to navigate a new future after a planned merger with cancer imaging company Kuva Labs fell apart.
Pfizer has axed two clinical-stage obesity programs, dropping a GLP-1 receptor agonist from the Metsera buyout and a GIPR antagonist as part of its quarterly pipeline cleanout.
A phase 2 trial of Merck & Co.’s anti-TL1A monoclonal antibody has missed its primary endpoint, closing off one avenue for expansion of an asset acquired in a $10.8 billion takeover. The setback was offset by a…
Not content with navigating Rezdiffra’s trajectory to blockbuster territory, Madrigal Pharmaceuticals has spent 2026 shopping for a range of drugs that the company hopes could work alongside its metabolic…
One of the most closely watched vacancies in biopharma has now been filled, with Sobi CEO Guido Oelkers, Ph.D., moving across to take up the top job at mRNA pioneer BioNTech.
Combining the two drugmakers would trigger severe regulatory concerns and significant pipeline disruptions, cost numerous jobs, all while damaging the broader biopharma ecosystem and hurting patients, Angus Liu argues in…
A phase 3 trial of Novo Nordisk’s ziltivekimab has missed its primary endpoint, denting the prospects of a molecule analysts tipped to generate blockbuster sales and diversify the company’s portfolio. Novo has chances to…
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