What's new in bioscience: research, preprints, clinical trials, funding and company moves. Global, with an India filter. Nothing here is hand-picked. The site collects and sorts itself, every day.
Updated · 160 items
Peer-reviewed papers. Global items come only from a whitelist of 46 core journals. A new paper has no citations yet, so where it published is the only quality signal available on the day it appears. India-affiliated work uses a wider net, because the local ecosystem mostly does not publish in Nature.
Post-harvest losses remain a critical challenge in global food systems, pressing the need for efficient and sustainable drying technologies to ensure food preservation and food loss reduction. The primary objective of this review is to study solar hybrid…
Background Surgical site infection (SSI) is the most common postoperative complication and leads to a poor prognosis. SSI triggers the acute-phase response, which leads to increased levels of high-sensitivity C-reactive protein (hsCRP) and myeloperoxidase…
Homocysteine and its vitamin cofactors are associated with vascular biology, but post-stroke measurements are vulnerable to confounding and reverse causation. This study compared serum homocysteine, vitamin B6, vitamin B12 and folate between adults with acute…
Abstract Background: Hostile surgical fields are irradiated, infected, or previously operated regions, characterized by fibrosis, loss of normal anatomical planes, and reduced tissue resilience. In such settings, critical structures may lie immediately beneath…
Incomplete spinal cord injury (iSCI) leads to significant motor impairments, affecting mobility and quality of life. Emerging rehabilitation strategies, including neuromodulation and virtual reality-assisted treadmill training, have shown potential in…
Community Medicine requires undergraduate medical students to integrate clinical reasoning with epidemiological interpretation, the social determinants of health, national health-programme linkage and preventive decision-making. Digital case-based learning…
Protein recognition mimicry is of great interest in the field of molecular bioengineering and rational design, with mutagenesis frequently employed to analyze the effects of altering amino acids involved in molecular recognition. The conformational and…
ABSTRACT High genetic variability in streptococci is driven by natural competence, specifically in Streptococcus pneumoniae and its close commensal species ( Streptococcus pseudopneumoniae , Streptococcus oralis , and Streptococcus mitis ), which drives rapid…
Carbohydrate-active enzymes (CAZymes) are a diverse group of enzymes produced by microbes, plants, and animals that play a central role in carbohydrate metabolism. Families of CAZymes, including GHs (Glycoside Hydrolases), GTs (Glycosyltransferases), PLs…
The composition of a polyclonal antibody response is hard to measure experimentally but contains vital information about the robustness of immunity. Here, we argue that the statistics of neutralization titers alone can be used to make quantitative predictions…
Aldabra giant tortoises ( Aldabrachelys gigantea ) are exceptionally long-lived. We sequenced the genome and methylome of Jonathan, a 194-year-old Aldabra, to explore the molecular basis of his longevity. Relative to other giant tortoises ( A. gigantea and…
Abstract Developmental dynamics involve the specification of diverse cell types and their spatial organization into multicellular niches 1 . Here we combine single-cell and spatial multiomics to define 21 distinct tissue niches in the developing heart, which…
The retina metabolizes glucose into lactate, a hallmark of aerobic glycolysis known as the Warburg effect. Although evidence points to rod photoreceptors as the primary source of aerobic glycolysis, a comparison of the energy metabolism in different retinal…
Chronic placental inflammation (CPI), an umbrella term encompassing chronic chorioamnionitis, chronic villitis, and chronic deciduitis, is associated with preterm birth (PTB), yet its cellular and molecular determinants across gestation remain poorly defined.…
Early-life nutrition shapes lifelong health, yet the long-term consequences of childhood overnutrition, particularly on musculoskeletal aging, remain unclear. Here, we show that neonatal overfeeding acts as a developmental insult that accelerates age-related…
Thymic macrophages (TMs) maintain tissue homeostasis by clearing the large numbers of apoptotic cells generated during T cell development, but how TM heterogeneity relates to their developmental origin and role in thymocyte maturation remains incompletely…
Abstract Citrobacter rodentium ( Cra ) infection, a murine model of enteropathogenic Escherichia coli (EPEC) infection, induces crypt proliferation that potentially promotes mucosal healing and pathogen clearance, yet the underlying molecular mechanisms remain…
Schistosomiasis, a neglected tropical disease caused by infection with parasitic blood flukes of the genus Schistosoma , affects more than 250 million people worldwide. Currently, patients rely on a single medicine, praziquantel (PZQ), discovered half a…
Regulatory T cells (Tregs) are essential for maintaining immune homeostasis and preventing autoimmune diseases, but are also a major cellular constituent of the tumor microenvironment (TME) that facilitates cancer progression. Identifying differences in Treg…
This population-based cross-sectional survey assesses hypertension prevalence and indicators of management and control in 2023 and compares these findings with a similar population-based survey conducted in 2011.
Microglia are the primary immune cells of the brain, but their role in Parkinson’s disease is not fully understood. Chronic microglial activation is toxic to neurons, but in the early stages of pathology, microglia also exert beneficial functions. We used…
Abstract TFIID is instrumental in recognizing promoter sequences and initiating transcription, yet a cohesive understanding of how this complex engages and functions at different promoter types in vivo is still lacking. Here, we employed ChIP-nexus to capture…
Most disease-associated genetic alterations do not affect the genes themselves, but instead change how strongly they are expressed, often by modifying genome accessibility. Gene expression and accessibility have now been analysed simultaneously in 10 million…
Herpes simplex virus 1 (HSV-1) infections of the central nervous system cause encephalitis and are associated with increased risk of neurodegeneration, yet the molecular consequences of lytic infection in human neurons remain incompletely defined. We map the…
Abstract Primate lentiviruses counteract antiviral APOBEC3 (A3) cytidine deaminases through virion infectivity factor (Vif), which recruits A3 proteins to a Cullin–RING E3 ubiquitin ligase for proteasomal degradation. While HIV-1 Vif is well characterized,…
Recurrent attractor networks are widely thought to form the basis of working memory1–3, but how they can be rapidly switched on and off is unclear4–7. Here we investigate stability and switching in a recurrent circuit of the fly navigation centre8. h∆K and PFG…
The evolution of complex brains required the incorporation of newly evolved neurons into existing circuits, yet the genetic and developmental mechanisms enabling their integration remain poorly understood. Butterflies expanded their color vision by adding a…
Abstract Interleukin 2 (IL2) promotes T cell proliferation and differentiation, making it a central target in immunotherapies. Following antigen recognition, IL2 receptor (IL2R) signaling polarizes towards the immunological synapse (IS). However, how IL2…
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bioRxiv and medRxiv, where new biology often lands months before the journal version. Not peer reviewed. Filtered on subject relevance rather than quality, since no quality signal exists at this stage.
Pancreatic ductal adenocarcinoma (PDAC) arises within an extensively remodeled microenvironment, yet tissue markers that distinguish invasive carcinoma from precursor lesions remain limited. Integrating four single cell RNA sequencing atlases comprising…
Human Ca2+/calmodulin (CaM)-dependent protein kinase II alpha (CaMKII) is a highly abundant and conserved protein in the brain. It is a multifunctional serine/threonine kinase that phosphorylates cellular substrates across subcellular compartments, activating…
Voltage-dependent facilitation (VDF) is a distinctive phenomenon of L-type voltage-gated calcium (CaV) channels, in which depolarized prepulse voltages increase inward current by up to several fold. Despite extensive study, the molecular origin and biophysical…
The SARS-CoV-2 nucleocapsid (N) protein is a 419-amino-acid modular protein essential for viral RNA replication, genome packaging, and host-cell modulation. It contains two structured domains, the N-terminal RNA-binding domain (NTD) and C-terminal dimerization…
BackgroundHereditary cancers account for approximately 5% to 10% of all malignancies and are more frequently observed in individuals with early-onset disease or a significant family history of cancer. However, large pan-India datasets describing germline…
Human and non-human animals often coordinate their behavior, a phenomenon thought to strengthen relationships by enabling sequential assessment of an interaction partners quality as a mate or rival, a process that directly affects evolutionary fitness. There…
Stopping antimicrobial multidrug resistance (AMR) is essential to maintain the efficacy of current treatments and sustain modern medicine, but current control relies on a coordinated One Health approach involving stewardship, infection prevention and other…
Aims: Atherosclerosis develops over many years, and its underlying mechanisms are still not fully understood. Studying plasma metabolites at different stages of the disease may help identify biomarkers that clarify how it develops and improve early risk…
Glaucoma endophenotyping is limited by disease heterogeneity and single-modality structural imaging. We introduce FORGE (Functionally guided OCT Representation for Glaucoma Endophenotyping), a cross-modal contrastive framework that uses visual field (VF)…
Purpose Open-source vision-language models (VLMs) can be locally deployed without external internet access. This study aimed to evaluate the slice-level lesion-detection performance of multiple general-purpose and medical-purpose open-source VLMs for brain…
Posttraumatic stress disorder (PTSD) after traumatic childbirth is a serious maternal morbidity that affects about 20% of women following medically complicated deliveries. Yet it often goes undetected in perinatal care, in part because brief screening tools…
Objective: Genes within the lysosomal glycosphingolipid pathway, including GBA1 and GALC, are important genetic risk factors in Parkinson's disease (PD). We hypothesized that PD risk relates not only to individual enzyme effects but also to coordination…
Abstract Background: In Pakistan approximately 7 million people were living with diabetes in 2014. To address the burden of diabetes, a randomized controlled trial was conducted to evaluate the effectiveness of a standardized care package in improving diabetes…
Background/ObjectivesOlder adults are at high risk of influenza-related severe disease and complications. HD-IIV, currently recommended for adults [≥]65 years, is egg-based and may be subject to egg-adapted mutations. An mRNA-based vaccine for influenza,…
Background. Large language models (LLMs) are increasingly used to automate title-abstract screening in systematic reviews, but validation studies typically report sensitivity, specificity, or Cohen's kappa: metrics that are unstable under the low and…
Human health is a single underlying state that no measurement observes directly. Diagnoses, blood tests, molecular profiles and images capture different facets at different times. Inferring health from such evidence requires a representation that integrates…
Medical large language models (LLMs) have shown promise in medical knowledge retrieval and clinical reasoning. However, their capacity for quantitative reasoning over dense, longitudinal health data remains limited, largely due to the lack of effective…
Abstract Objectives To conduct a Delphi process to inform an international, consensus definition of manuscript peer review. Design Three-round Delphi consensus study including two surveys and one virtual consensus meeting. Peer review features identified…
Background: Hepatitis E virus (HEV) is highly endemic in several African countries with high mortality rate among pregnant women. The prevalence of HEV in Niger among pregnant women is unknown. We hereby aim to report the prevalence and risk factors of HEV…
Pulmonary tuberculosis (TB) is associated with systemic alterations extending beyond the lungs, yet the longitudinal impact of anti-tuberculosis therapy (ATT) on gut ecosystem recovery remains poorly understood. Here, we performed a longitudinal multi-omics…
Background and objectives: Industrialisation is associated with lower gut microbial richness. The ecological insurance hypothesis proposes that richer communities buffer disturbance via overlapping functions, possibly affecting infection susceptibility. We…
Background: Amplicon-based next-generation sequencing is a cornerstone of viral genomic surveillance, but it often produces datasets with highly uneven read coverage due to PCR amplification bias. This leads to excessive data generation and substantial…
Foundation models for colour fundus photography (CFP) are candidate visual encoders for multimodal medical AI, but existing models are large and are assessed under fine-tuning rather than the frozen-encoder conditions such systems impose. We present RFM…
Background: Excess mortality estimates depend on an expected baseline, an unobservable quantity typically derived from models with prescribed functional forms and short reference periods that exclude exceptional events. Singular Spectrum Analysis (SSA) offers…
Background: Circulating proteins are promising biomarkers of colorectal cancer risk. Most studies combine colon and rectal cancer despite their biological differences. Objective: To identify proteins associated with colorectal, colon, and rectal cancer risk…
Background: COVID-19 vaccination uptake is influenced by various sociodemographic and psychological factors. Previous studies have suggested that the relationship between personality traits and vaccination is context-dependent. However, this association has…
Background Exposure-history data collected during epidemics or pandemics within digital contact-tracing applications hold immense potential for rapid, scalable epidemiological inference. The sensitivity of these data makes privacy-preserving designs essential…
Identifying progressive dementia during its prodromal stage is a challenging yet critical task for healthcare providers. Traditional clinical assessments are often not sensitive enough to detect warning signs of cognitive decline. Machine learning (ML) methods…
PURPOSEHow sarcoma subtypes engage telomerase versus alternative lengthening of telomeres (ALT), and with what consequence, is incompletely defined. METHODSWe analyzed 11,792 patients with sarcoma sequenced across 19 centers in AACR Project GENIE v20.0.…
Phylodynamics bridges the gap between epidemiology and pathogen genetic data. The birth-death (BD) model and its extensions serve to infer the average number of secondary infections R and the infection duration d from time-scaled pathogen phylogenies.…
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Phase 2 and 3 interventional studies from ClinicalTrials.gov. One real limit worth knowing: Indian trials mostly register with CTRI, not CT.gov. So "India" here means a global study running Indian sites, which is where large pharma touches India. Reading CTRI is the next thing to add.
The purpose of this study is to evaluate the efficacy of lepodisiran in reducing cardiovascular risk in participants with high lipoprotein(a) who have cardiovascular disease or are at risk of a heart attack or stroke. The study drug will be…
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease…
The purpose of this study is to evaluate the effect and safety of orforglipron once daily in participants with Fontaine II peripheral arterial disease (PAD). Participation in the study will last about 58 weeks.
A global study to assess the efficacy and safety of durvalumab in combination with bevacizumab or durvalumab alone in patients with hepatocellular carcinoma who are at high risk of recurrence.
The purpose of this study is to measure cardiovascular outcomes with orforglipron compared with placebo in participants with atherosclerotic cardiovascular disease (ASCVD) and/or chronic kidney disease (CKD). Participation in the study will…
The main purpose of this study is to assess if different dose levels of Brenipatide are safe and work the way they are intended to work in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), when compared with…
The purpose of this study is to assess the safety and efficacy of brenipatide at different dose levels compared with placebo in participants with moderate-to-severe asthma. Study participation will last approximately 65 weeks, including…
The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people with high-risk metabolic dysfunction-associated steatotic liver disease (MASLD). The…
The main purpose of this study is to evaluate the efficacy and safety of eloralintide compared with placebo for body weight reduction in participants with overweight or obesity and type 2 diabetes. Participation in the study will last about…
The main purpose of the study is to evaluate the effectiveness and safety of LY4268989 when given with mirikizumab compared to mirikizumab alone in adult participants with moderately to severely active ulcerative colitis (UC). Study…
This study is being done to find out if a new medicine called PF-08634404, when given with chemotherapy, works better than the present standard treatment (pembrolizumab with chemotherapy) for adults with a type of lung cancer called…
This study will evaluate the efficacy and safety of orforglipron in participants with overweight and assess whether it helps reduce the future risk of obesity-related conditions, including type 2 diabetes, hypertension, and dyslipidemia,…
The purpose of the studies is to evaluate the efficacy and safety of eloralintide in participants with moderate-to-severe obstructive sleep apnea and obesity or overweight. YDAO is a master protocol designed to support two independent…
The main purpose of this study is to evaluate the safety and effectiveness of LY4268989 when compared to placebo in adult participants with moderately to severely active ulcerative colitis (UC). The study drug will be administered orally.…
The purpose of this study is to test the efficacy and safety of orforglipron in participants with T2D (type 2 diabetes) who participate in fasting during Ramadan. For each participant, the study will last up to 48 weeks with a minimum of 7…
The main aim of this study is to find out how well elritercept works in lowering the need for RBC transfusions. Other aims are to learn how well elritercept works in reducing the need for RBC transfusions over longer periods of time or in…
The main purpose of this study is to determine if retatrutide can significantly lower the incidence of serious heart-related complications or prevent the worsening of kidney function. The trial will enroll adults with body mass index 27…
This study aims to evaluate the antitumor activity and safety of JDQ443 single-agent as first-line treatment for participants with locally advanced or metastatic non-small cell lung cancer (NSCLC) whose tumors harbor a KRAS G12C mutation…
The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult female participants with stress urinary incontinence (SUI) who have obesity or…
The purpose of this study is to evaluate izalontamab brengitecan (iza-bren) combined with osimertinib in participants with previously untreated, locally advanced or metastatic EGFR-mutant NSCLC, compared to osimertinib alone or osimertinib…
The goal of this trial is to accelerate the development of pharmacological therapies for critical illness by identifying biological sub phenotypes in patients with acute respiratory distress syndrome (ARDS). The trial will stratify…
Background: \- People who have an allogeneic hematopoietic stem cell transplant (HSCT) need help as they recover. Being a caregiver can be stressful to the body and mind. Researchers want to find ways to reduce this stress. Objective: \- To…
The goal of this clinical trial is to learn if an herbal supplement called Biocidin REMOVE can clear small intestinal bacterial overgrowth (SIBO) in adults with irritable bowel syndrome (IBS). SIBO means there are too many bacteria in the…
This study will assess the efficacy, safety, optimal dose and ADA and NAbs development of TRK-950 at two separate dose levels in combination with ramucirumab and paclitaxel (RAM+PTX) as compared with RAM + PTX treatment alone in…
This study is being conducted to assess whether the study medicine PF 08634404, given in combination with chemotherapy, improves outcomes compared with another medicine called pembrolizumab plus chemotherapy. Chemotherapy is a type of…
The primary purpose of the study is to evaluate the efficacy of olezarsen administered by subcutaneous injection to pediatric participants with FCS.
Multicenter, prospective, open-labeled, 2-arm, non-comparative randomized phase II trial to assess the antitumor activity of retifanlimab (INCMGA00012) in association with neoadjuvant chemotherapy
This compares the effects of nivolumab at a fixed dose of 40 mg with chemo-immunotherapy versus chemo-immunotherapy alone in treating patients with newly diagnosed primary mediastinal B-cell lymphoma (PMBCL). Immunotherapy with monoclonal…
Background: Shingles is a painful, blistering rash caused by the same virus that causes chickenpox. Shingrix is a vaccine approved to prevent shingles in healthy adults over age 50 and in immunocompromised adults over age 18. Researchers…
Background: Oncocytic (Hurthle cell) thyroid cancer (HTC) is a rare disease with few treatment options. Researchers are developing a radioactive drug that targets a protein that appears in high numbers on HTC cancer cells. Objective: To…
The purpose of this study is to learn about the effects of study medicine (PF-08634404) when given alone or with another antibody (ipilimumab) for the treatment of a type of liver cancer called hepatocellular carcinoma (HCC) that is either…
This is a prospective, single-center, single-arm Phase II pilot study designed to evaluate the efficacy and safety of FMT in combination with QL1706 and Bevacizumab as first-line treatment for advanced Hepatocellular carcinoma.
The purpose of this study is to compare the effects of Virtual Reality-Reward Training (VR-RT) with an active control condition, Virtual Reality-Memory Training (VR-MT), on positive affect and other clinical symptoms. VR-RT is a novel…
The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.
WP44714 is a Phase I/II, open-label, non-randomized, global, multicenter trial consisting of two parts: * Part 1 is a multiple-ascending dose (MAD) study in adult and adolescent male participants with severe or moderate hemophilia A with or…
This study evaluates the effect of ROC-101 in adults with either Pulmonary Arterial Hypertension (PAH) or Pulmonary Hypertension Associated with Interstitial Lung Disease (ILD-PH). Each eligible participant will receive standard of care…
Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess change in disease activity when telisotuzumab adizutecan is given alone compared to standard of care (SOC) given…
This phase III trial studies how well metformin hydrochloride works compared to placebo in preventing breast cancer in patients with atypical hyperplasia or in situ breast cancer. Chemoprevention is the use of certain drugs to keep cancer…
The purpose of this trial is: * To investigate whether cannabidiol (CBD), compared to placebo, can reduce the severity of attenuated psychotic symptoms in individuals at clinical high risk for psychosis. * To confirm the safety of CBD in…
Researchers are looking for new ways to treat metastatic castration-resistant prostate cancer (mCRPC). Researchers have designed a study medicine called ifinatamab deruxtecan (also called I-DXd or MK-2400) to treat mCRPC. The goal of this…
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Rounds, approvals, launches and company moves from 13 trade and business feeds. Specialist bioscience outlets pass through. General business feeds have to earn their place on a keyword in the headline.
Healthcare industry reported 85 deals worth $6.2 billion in September 2026, while VC funding increased by 21.6% to $4.2 billion The post Pharma deal value falls 78.8% in September 2026: GlobalData appeared first on…
Dehradun-based medtech startup Sunfox Technologies has raised $7 Mn (around ₹67 Cr) in a Series A funding round led by…
Funding across HealthTech, Life Sciences and Healthcare sectors stood at $256.7M across 22 rounds The post India pharma and healthcare funding falls to $256.7M in September 2026 appeared first on Express Pharma .
The product is indicated for the treatment and prophylaxis of hypoprothrombinemia and vitamin K deficiency The post Lupin receives USFDA approval for Phytonadione Injectable Emulsion appeared first on Express Pharma .
Suneela Thatte, VP & Head, Merck Healthcare R&D India in an exclusive conversation with Swati Rana, speaks about the skills the next generation of R&D professionals will need, the role of universities and industry…
The Kerala government will upgrade its Ayurveda hospitals and address the shortage of therapists, Minister K Muraleedharan said. Speaking after inaugurating the district-level celebrations of the 11th Ayurveda Day at…
The research paper, titled "Green-light-activated Os(II) metallophotoantibiotics for antibacterial therapy and infected wound healing," presents a promising scientific approach to addressing some of the major challenges…
Christoph Funke, Chief Technical Operations Officer, Lupin, explains why India’s pharma industry needs to look beyond its cost advantage. He outlines how manufacturing intelligence, supply-chain resilience and stronger…
Indigenous alternatives to imported medical technology are taking shape through additive manufacturing (AM), as the Ministry of Electronics and Information Technology (MeitY) backs new medical device manufacturers under…
Medical suppliers have restricted supplies to the MNJ Institute of Oncology and Regional Cancer Centre in Hyderabad over pending payments, with only emergency requirements being met, according to the Telangana Hospitals…
In a significant achievement, scientists at the Indian Institute of Technology, Varanasi (BHU) published their research on an innovative light-activated antibacterial technology in Communications Chemistry, a prestigious…
Keralam Chief Minister VD Satheesan said the government had allocated over ₹600 crore as additional funds for Karunya health schemes to clear pending claims. According to a statement issued by the Chief Minister’s…
The Centre seems to be adamant that Keralam should not not be given an All India Institute of Medical Sciences (AIIMS) because at different times it has cited different reasons for refusing AIIMS to the State, Health…
Union Minister for Health and Family Welfare, Jagat Prakash Nadda, launched JOSH (Joint Squad for Health) Teams under the TB Mukt Bharat Abhiyaan at a national event held at Bharat Mandapam, New Delhi, marking a…
Medical e-waste is emerging as a global challenge, with much of it not being recycled due to concerns over contamination, according to a study by the Waste Electrical and Electronic Equipment (WEEE) Forum. Electronic…
The Trump administration has finalized new healthcare price transparency regulations in an effort to allow Americans more clarity about their medical costs. The rules, posted Oct. 5, strengthen the federal Transparency…
UPES today inaugurated the World Congress on Health Sciences and Technology 2026 at its Bidholi campus in Dehradun, bringing together leading researchers, clinicians, healthcare professionals, policymakers, innovators…
The Food Safety and Standards Authority of India (FSSAI) said the product was advertised as providing high-protein support for preserving lean muscle during GLP-1/GIP therapies, commonly used in weight-loss treatment.
Water shortage likely due to the continued impact of El Nino, says State Agriculture Minister Tummala Nageswara Rao
India's TB incidence, he noted, has declined by 21 per cent compared with a 12 per cent global decline, while the country's treatment coverage has reached 92 per cent against 78 per cent globally, and called for a "last…
A bench of Chief Justice Soumen Sen and Justice V M Syam Kumar further queried whether the large number of private hospitals in the state was a disqualification for establishing an AIIMS in Keralam.
Russia's health watchdog said on Tuesday that no cases of plague had been detected among anyone who had come into contact with the deceased worker, Darya Shipilova, and a local official said that 60% of those placed in…
The packaging system combines moisture and oxygen barrier protection with design for recyclability for pharmaceutical applications The post ACG launches RecycloPod PP Ultra polypropylene blister packaging system appeared…
Ashwin Sapra, Partner Life Sciences and Healthcare, Trilegal shares a critical examination of the proposed amendment to the Drugs Rules, 1945 The post CCTV at pharmacies: Is surveillance enough to curb unauthorised drug…
The agreement will facilitate scientific exchanges and collaborative projects while addressing crop production, processing, value addition and post-harvest losses
Iambic Therapeutics is aiming to raise $135 million in net proceeds from an IPO as the AI biotech looks to fund the clinical development of its lead cancer drug.
Investment firm TCGX is expanding in Asia, raising $600 million to funnel into biotechs emerging from a burgeoning drug discovery hotspot.
Matchpoint Therapeutics has aced its series B round, serving up $150 million to advance the Sanofi-backed biotech’s pipeline of precision covalent medicines.
The Fierce Biotech Fundraising Tracker records venture capital rounds of $50 million or more secured by biotechs.
Endeavor BioMedicines solidified its potential threat to Big Pharma with a phase 2b readout suggesting its Hedgehog inhibitor could become the first drug to reduce lung fibrosis while increasing total lung capacity.
Vacancy rates for lab and manufacturing spaces in Massachusetts increased 11-fold to 31% between 2021 and 2026. So what's gone wrong?
Japan’s Ono Pharmaceutical is paying $80 million upfront for the regional rights to a trio of Biohaven’s IgG degraders, led by a phase 3-stage Grave’s disease prospect.
Zealand Pharma has reported more phase 2 data on its Roche-partnered amylin analog, linking the drug candidate to competitive weight loss but a lackluster effect on blood sugar.
A phase 2 celiac disease trial of argenx’s FB102 has hit its primary endpoint, delivering a boost to a drug candidate that the biotech acquired in its $2.2 billion takeover of Forte Biosciences.
Cadrenal Therapeutics, a heart-focused biotech that recently reached an agreement with the FDA on the design of a pivotal trial for its lead candidate, is now instead looking to offload its pipeline or potentially the…
As always, if you know of layoffs occurring at a biotech, please reach out to the Fierce Biotech editorial team.
The U.S. Department of Health and Human Services announced the launch of a new program aimed at removing barriers that slow clinical development and transforming how clinical trials are designed and conducted.
Cerevance's oral non-dopaminergic therapy has redeemed itself by improving both motor and non-motor symptoms in a phase 3 Parkinson's disease study.
Atsena Therapeutics has reported evidence of efficacy in a clinical trial of an eye disease gene therapy, encouraging the biotech to forge ahead with a study that could support a filing for approval in 2028.
MimiVax has reports a phase 2b miss in newly diagnosed glioblastoma patients, but remains positive about a significant survival benefit in a subset of patients 65 years and under.
The Bay Area biotech is discontinuing all clinical development activities and implementing a "substantial reduction in workforce."
Stryker veteran Spencer Stiles will take up the chief executive role as its former CEO Kevin Lobo will move into the boardroom.
Big Pharma-backed Nuvig Therapeutics has halted one of the two trials for its sole clinical asset after determining the program wouldn’t be able to advance quickly enough.
Abbott has been given U.S. clearance for new updates to its CardioMEMS HF System that allow for patient-facing capabilities through its CardioGuide HF App.
While psychedelic drugs may be capturing all the attention when it comes to finding fresh ways to treat neuropathic pain, research with mice has suggested a peptide approach may also be effective.
A phase 3 lung cancer study of ArriVent BioPharma’s EGFR inhibitor has missed its primary endpoint, sending the biotech’s stock down 57% in early trading on the Nasdaq.
Kairos Pharma is moving prostate cancer prospect ENV-105 into an earlier line of treatment in response to midphase survival data.<br>
Forbion has touted its “landmark” 2.3 billion euro ($2.6 billion) fundraise across two funds as a new record for the European life sciences-focused VC firm.
The U.K.’s drug and medical technology regulatory body the MHRA will continually monitor all artificial intelligence-based devices.
In the past 18 months, the National Institutes of Health has been working overtime to push new policies to reduce animal testing with the help of one woman at the helm: Nicole Kleinstreuer, Ph.D.
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