What's new in bioscience: research, preprints, clinical trials, funding and company moves. Global, with an India filter. Nothing here is hand-picked. The site collects and sorts itself, every day.
Updated · 160 items
Peer-reviewed papers. Global items come only from a whitelist of 46 core journals. A new paper has no citations yet, so where it published is the only quality signal available on the day it appears. India-affiliated work uses a wider net, because the local ecosystem mostly does not publish in Nature.
Antibiotic development has historically been concentrated in high-income countries. We discuss how India is emerging as an important centre for antimicrobial development, and the implications for global health and equity of access to life-saving therapies.…
<title>Abstract</title> Crop yield prediction plays a very important role in productivity growth. Prediction of the crop yield in particular area helps the farmer to choose the right crop to be grown in the land. With crop yield prediction crop recommendation…
PURPOSE: To determine the prevalence of visual field (VF) defect among Indian driving licence (DL) holders and to evaluate their eligibility according to UK Driver and Vehicle Licensing Agency (DVLA) visual fitness standards. METHOD: Design: This…
Objective: To determine the incidence of and factors associated with magnetic resonance imaging (MRI)-detected postoperative spinal epidural hematoma after single-level unilateral biportal endoscopic (UBE) lumbar decompression with or without discectomy, and…
Tuberculosis of the craniovertebral junction (CVJ) is an uncommon condition, particularly in the pediatric population, and may present with severe neurological deficits due to instability and spinal cord compression. Surgical management is especially…
Importance: Elevated low-density lipoprotein cholesterol (LDL-C) is a modifiable risk factor for cardiovascular disease, the leading cause of premature death worldwide. Assessing the LDL-C-related burden is critical for guiding prevention and treatment…
Background: The cerebrospinal fluid tap test (CSF-TT) is widely used as an ancillary test to identify patients with idiopathic Normal Pressure Hydrocephalus (iNPH) for surgical management; however, its diagnostic utility remains unclear. We evaluate the…
Abstract Introduction Resistance to Mycobacterium tuberculosis (Mtb) infection despite known exposure varies among individuals, but the molecular mechanisms underlying this resistance remain poorly understood. It is unclear whether microRNAs (miRNAs) influence…
IntroductionAdenomyomatous hyperplasia (AH) of the Vaterian system is a rare benign lesion, often clinically mistaken for carcinoma and leading to unnecessary Whipple surgery.MethodsIn this multicentre cohort, Whipple pancreaticoduodenectomy specimens were…
The skin colour is determined by melanin which is the brownish black pigment of Melanocytes. It is produced through melanogenesis. The melanin is crucial for protection of DNA from UV damage and it absorbs excess radiation. Skin pigmentation-related disorders…
Crossovers (COs) ensure proper chromosome segregation during meiosis and generate genetic diversity. COs are non-uniformly distributed along chromosomes and almost universally suppressed in centromere-proximal regions, notably creating an important bottleneck…
Abstract Understanding the complex interplay between gene expression and neuronal activity is crucial for unraveling the molecular mechanisms underlying cognitive function and neurological disorders. Here, we developed pooled screens using CRISPR interference…
Preterm birth (PTB) remains a major pregnancy complication, yet the role of the maternal gut virome in its etiology is largely unknown. Here we show that the maternal gut virome undergoes ecological destabilization prior to PTB, coupled with distinct host…
Abstract Macrophages are critical effectors of antibody therapies for lymphoma, but the best targets to engage their function remain unknown. Here, we develop a ‘tactical surfaceome profiling’ strategy to define a comprehensive repertoire of surface antigens…
Abstract Hyperglycemia and its related diseases, such as diabetes, dramatically accelerate cancer progression. However, the underlying mechanisms remain poorly understood, and the development of anticancer therapies based on them has largely stalled.…
Idiopathic pulmonary fibrosis (IPF) is a progressive, fatal disease lacking clarity on the mechanisms linking epithelial injury to fibrotic remodeling. Here, we identify the microbiota-derived corisin as a potent, multifaceted driver of epithelial injury and…
Perennial leguminous shrubs of the genus Caragana play key roles in arid and semi-arid ecosystems, contributing to ecological restoration, nitrogen fixation, and bioenergy production. However, the genomic basis underlying their adaptation to arid environments…
Abstract Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED/APS-1) is a monogenic disorder of failed central tolerance. Interferon-γ-driven inflammation in APECED underlies multiorgan autoimmunity and chronic mucocutaneous candidiasis and…
LINE-1 (L1) retrotransposition is common in human cancers and rearrangements at insertion sites can contribute to cancer-driving oncogene amplifications and promote genome instability. However, the mechanisms underlying rearrangements of L1 retrotransposition…
L-(+)-tartaric acid (L-TA) is a high-value chiral organic acid essential for food and pharmaceuticals. Despite its industrial importance, sustainable green production is constrained by the lack of a fully defined biosynthetic pathway. Here, we report the de…
Long-term exposure to ultraviolet (UV) radiation can cause sunburn, skin aging, and skin cancers. Conventional sunscreens typically combine organic UV filters and inorganic particles for photoprotection, yet concerns remain regarding skin penetration, systemic…
Escherichia coli sequence-type 131 (ST131) is the dominant global extraintestinal pathogen capable of asymptomatic intestinal carriage and sustained household transmission, challenging infection control. Despite its clinical significance, the ecological…
In the last decade, an unexpectedly large number of translated regions (translons) have been discovered using ribosome profiling and proteomics. Translons can act as regulatory elements or encode functional micropeptides. However, identification of translons…
Atherosclerosis (AS) is the most important pathological basis for cardiovascular diseases worldwide. However, the current mainstream therapeutic strategies for AS only target isolated pathological links, ignoring hepatic steatosis as a related risk factor for…
Caveolae are flask-shaped invaginations of the plasma membrane serving critical functions in mechano-protection and signal transduction. Caveolar dynamics, such as caveolar movement within the plasma membrane or endocytosis, relies on precise shaping of the…
In eukaryotes, transcription factors (TFs) must continuously compete with nucleosomes to access their binding sites, leading to cell-to-cell variability in chromatin accessibility at regulatory regions. Although critical to understand enhancer function in…
Neurotechnologies are transforming how we measure, interpret, and modulate brain-body interactions, integrating real-time sensing, computation, and stimulation to enable precise physiological control. They hold transformative potential across clinical and…
Celery (Apium graveolens) is a globally cultivated vegetable renowned for its health-promoting and nutraceutical benefits. Exploring its genomic and metabolic diversity can help to facilitate breeding selection. Here, by integrating genomic and metabolomic…
Cells have evolved sophisticated molecular and cellular mechanisms to cope with stress. While these stress programs are vital, their overactivation as well as spurious activation in non-stress conditions must be prevented. The mechanisms enforcing this…
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bioRxiv and medRxiv, where new biology often lands months before the journal version. Not peer reviewed. Filtered on subject relevance rather than quality, since no quality signal exists at this stage.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease influenced by genetic and environmental factors, including diet. We examined the associations of dietary inflammatory potential, dietary diversity, and micronutrient adequacy with RA and…
Osteoarthritis (OA) is increasingly recognized as a whole-joint disease, yet eQTL studies have focused almost exclusively on cartilage. Here we build cell-type-resolved gene regulatory maps of human synovium and infrapatellar fat pad (IPFP), integrating…
Shilajit is a naturally occurring resinous exudate with centuries of documented use in Ayurvedic medicine. Its principal bioactive constituents -- fulvic acid and a proprietary aromatic compound complex termed shilarathenes, comprising urolithin metabolites,…
Background Hereditary cancers account for approximately 5% to 10% of all malignancies and are more frequently observed in individuals with early-onset disease or a significant family history of cancer. However, large pan-India datasets describing germline…
IntroductionThe acquisition of National Institutes of Health (NIH) grants is an increasingly competitive undertaking. Many early-career biomedical investigators lack sufficient grant writing skills. This pragmatic, 2x2 factorial, group-randomized trial tested…
Bacterial microcompartments (MCPs) are versatile proteinaceous organelles that compartmentalize metabolic pathways, offering promising scaffolds for synthetic biology and metabolic engineering. However, designing customized nanobioreactors requires…
Public metabolomics repositories contain thousands of studies, but differences in metadata structure, vocabulary, and repository-specific terms still limit reliable search, comparison, and reuse within and across databases. Here we present HARMONY, an…
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Apple scar skin disease (ASSD), caused by Apple scar skin viroid (ASSVd), is characterized by peel scarring, cracking, dappling, and fruit deformation, resulting in reduced fruit quality and marketability. Despite its economic importance, the physicochemical…
Pathogenesis inflicted by Entamoeba histolytica causes amoebic diarrhea and liver abscesses and is one of the leading causes of mortality from parasitic disease worldwide. Preventive therapeutics in the form of a vaccine could be highly effective at providing…
Introduction: Malaria during pregnancy is a major risk factor for low birth weight (LBW) in newborns, which in turn negatively affects the growth and development of the child. The World Health Organization (WHO) recommended interventions for pregnant women…
Background: High-quality, longitudinal data from the Emergency Department (ED) are essential for understanding acute illness trajectories and for developing clinically deployable prediction models. However, most existing ED datasets are static, limited in…
The 2020 SARS-CoV-2 pandemic renewed global interest in wastewater-based epidemiology (WBE) as a tool for monitoring public health. Molecular analyses of wastewater are often limited by the small volumes of wastewater that can be processed, due to column…
Maternal depressive symptoms are a major public health concern in low- and middle-income countries (LMICs), yet evidence on their relationship with early childhood development (ECD) remains mixed. This study examined the association between maternal depressive…
While the public perceives e-cigarettes as less harmful than combustible tobacco, little is known about their specific health concerns regarding vaping. We demonstrate a data-driven strategy to discover the public's health concerns about vaping e-cigarettes…
A global pandemic requires accelerated strategies to mitigate public healthcare risks and preserve societal stability, either by repurposing existing drugs or by rapidly developing novel drug candidates. Computational platforms have accelerated candidate…
Background: In the age of TikTok, YouTube, and Netflix, video streaming (VS) is highly popular among adolescents. Yet, risky to addiction-like viewing patterns (i.e., problematic (P)VS) may adversely affect well-being. Prevalence estimates based on established…
Background Deconfliction is a central pillar of humanitarian risk mitigation in contemporary armed conflicts. Intended as a notification system through which parties to a conflict can mitigate against harm to humanitarian personnel and infrastructure, its…
Objectives To assess the effects of 24 weeks active treatment with baricitinib, a JAK1/2 inhibitor, in adult idiopathic inflammatory myopathy (IIM). Methods Patients with active dermatomyositis (DM) or polymyositis (PM) were enrolled into a 1:1 randomized…
Viral infections remain a cause of substantial morbidity and mortality in allogeneic hematopoietic cell transplant (aHCT) recipients. While antiviral prophylaxis has dramatically reduced the risk of herpes simplex virus (HSV) disease, the relationship between…
Background: White matter hyperintensities (WMH) represent the most visible manifestation of cerebral small vessel disease and of white matter pathology more broadly, yet empirical evidence points to a brain tissue injury extending beyond radiologically…
Background Spontaneous intracerebral hemorrhage (ICH) is the most devastating type of stroke but lacks the established time-critical treatment guidelines available for acute ischemic stroke. This study investigated the impact of Code Stroke activation and…
Objectives The cost-effectiveness of new amyloid-targeting therapies (ATTs) for patients with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease (AD) is influenced by assumptions about treatment effectiveness beyond the trial…
Self-determination has been assessed as an internal psychological construct. External factors may also affect self-determination, but opportunities to make choices and decisions remain understudied. We developed and evaluated the AASPIRE-Choices and Decisions…
Background and Hypothesis: Psychotic disorders are increasingly recognized as the extreme end of a broader psychiatric continuum, with less afflicted stages including the non-help-seeking familial high-risk state (FHR), the help-seeking clinical high-risk…
Effective infectious disease response requires region-specific guidance, because the contact structures that drive local transmission and shape intervention effects vary from community to community. Agent-based models (ABMs) represent these structures and the…
Human body temperature is sexually dimorphic, with females averaging 0.1-0.5{degrees}C warmer than males. Body temperature is also linked to immune responses through highly conserved fever and heat shock pathways. We hypothesized that subtle temperature…
Anhedonia and motivational impairment are central features of major depressive disorder, yet the neural processes linking reward information to sustained goal-directed behaviour remain insufficiently understood. Using functional magnetic resonance imaging, we…
Altered lipid metabolism is increasingly recognized as a feature of aging and age-related disease, including cancer. Here, we present a lipid-based biological aging clock developed from serum lipidomics data of 443 patients with pancreatic ductal…
SARS-CoV-2 transmission is highly overdispersed, with a minority of individuals responsible for the majority of transmission, though the drivers of this heterogeneity are unclear. Here, we assess the contribution of variation in viral load and daily contact…
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Phase 2 and 3 interventional studies from ClinicalTrials.gov. One real limit worth knowing: Indian trials mostly register with CTRI, not CT.gov. So "India" here means a global study running Indian sites, which is where large pharma touches India. Reading CTRI is the next thing to add.
The purpose of this study is to evaluate whether milvexian compared to placebo reduce the risk of recurrent ischemic stroke.
The purpose of this protocol is to evaluate the efficacy (how well it works), safety and tolerability of oral icotrokinra as therapy in adult and adolescent participants with moderately to severely active ulcerative colitis (UC, a chronic…
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as confirmed by…
The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a long-term condition causing severe inflammation of…
The purpose of this study is to evaluate the efficacy and safety of JNJ-78934804 as compared to guselkumab and golimumab in participants with moderately to severely active ulcerative colitis who have had an inadequate initial response, loss…
This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab versus RT±cetuximab in treatment-naïve,…
The purpose of study is to compare bladder intact-event free survival (BI-EFS) in participants receiving TAR-200 in combination with intravenous (IV) cetrelimab versus concurrent chemoradiotherapy.
This is a multicenter, randomized, double-blind, placebo-controlled parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth…
The purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chemotherapy with 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin,…
The purpose of this study is to compare anti-tumor activity of amivantamab in addition to pembrolizumab and carboplatin versus pembrolizumab, 5-fluorouracil (FU), and platinum therapy (carboplatin or cisplatin) in participants with…
The purpose of this study is to evaluate the efficacy of icotrokinra compared to placebo in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.
Participants include men and women ≥ 40 years of age with T2DM, established CV disease, a history of HTN with an SBP of at least 130 mmHg at screening, who meet the predefined serum potassium level, and with at least one additional risk…
The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the…
The purpose of this study is to evaluate how well JNJ-79635322 works when compared with teclistamab.
The purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall survival), when treated with amivantamab and chemotherapy with…
The purpose of this study is to evaluate the efficacy and safety of IV antifrolumab in adult patients with Active Proliferative Lupus Nephritis
The purpose of this study is to evaluate the efficacy of icotrokinra (JNJ-77242113) compared to placebo in biologic-experienced and biologic-naive participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and…
Nerandomilast is being developed to help people with systemic sclerosis by potentially improving symptoms and slowing disease progression. This study is open to adults who are at least 18 years old and have systemic sclerosis (SSc). People…
The purpose of this study was to compare the virologic efficacy and safety of three antiretroviral (ARV) regimens, dolutegravir plus emtricitabine/tenofovir alafenamide, dolutegravir plus emtricitabine/tenofovir disoproxil fumarate, and…
This open-label extension study will provide post-trial access to pelacarsen (TQJ230) to participants who have successfully completed the double-blind parent study (CTQJ230A12301).
This phase II trial compares the effect of dabrafenib and trametinib given continuously to given with a break in treatment (intermittent) in treating patients with stage III-IV melanoma that cannot be removed by surgery and contains a B-Raf…
This is a multicenter, open-label, dose-finding trial using a backfill Bayesian optimal interval (BF-BOIN) design to determine the maximum tolerated dose (MTD) and/or recommended phase 2 dose (RP2D) for paclitaxel oral solution combined…
This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients aged 5 to 17 years with a primary diagnosis of irritability associated with Autism Spectrum Disorder (ASD) based on Diagnostic and Statistical…
Primary Objective: To evaluate the efficacy and safety of perioperative oral terbinafine in reducing the incidence of cardiac surgery-associated acute kidney injury (CSA-AKI).Secondary Objectives:To assess the effects of terbinafine on the…
This phase III trial studies how well chemotherapy and radiation therapy work with or without atezolizumab in treating patients with localized muscle invasive bladder cancer. Radiation therapy uses high energy rays to kill tumor cells and…
This phase III trial studies how well pembrolizumab works compared to standard of care observation in treating patients with stage I-III Merkel cell cancer that has been completely removed by surgery (resected). Immunotherapy with…
This phase III trial compares the effect of adding immunotherapy (brentuximab vedotin and nivolumab) to standard treatment (chemotherapy with or without radiation) to the standard treatment alone in improving survival in patients with stage…
The purpose of the study is to separately assess the potential of dexamethasone, montelukast and methotrexate administration, prior to amivantamab infusion given through a needle in the vein, to decrease the incidence and/or severity of…
This phase II trial tests whether decitabine and cedazuridine (ASTX727) in combination with venetoclax work better than ASTX727 alone at decreasing symptoms of bone marrow cancer in patients with chronic myelomonocytic leukemia (CMML),…
The purpose of this study is to assess the ability to slow down or stop the growth of cancer with amivantamab combined with either lazertinib or chemotherapy (carboplatin and pemetrexed) in participants with resectable, epidermal growth…
Cancer is a condition where cells in a specific part of the body grow and reproduce uncontrollably. Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow (the spongy tissue inside the bones) that affects white blood cells…
This phase III trial compares the effect of adding cetuximab to pembrolizumab versus pembrolizumab alone in treating patients with head and neck squamous cell carcinoma (HNSCC) that has come back after a period of improvement (recurrent)…
This study will investigate if nivolumab will improve recurrence-free survival (RFS) compared to placebo in participants with HCC who have undergone complete resection or have achieved a complete response after local ablation, and who are…
The goal of this clinical trial is to learn if Elemene Liposomes, combined with carboplatin and paclitaxel (TC) chemotherapy can improve prognosis in patients with advanced or recurrent endometrial cancer. The main question it aims to…
This phase II trial compares the effect of chemotherapy (carboplatin and paclitaxel) with versus without cemiplimab given before surgery (neoadjuvant) in patients with sinonasal squamous cell cancer. Carboplatin is in a class of medications…
The purpose of this study is to evaluate how well nipocalimab works as compared to placebo in participants with moderate to severe Systemic lupus erythematosus (SLE, a long-term disease where the immune system mistakenly attacks its own…
This randomized phase II trial studies how well paclitaxel with or without cixutumumab works in treating patients with esophageal cancer or gastroesophageal junction cancer that has spread to other places in the body (metastatic). Drugs…
This phase I/II trial studies the effects of trastuzumab deruxtecan (DS-8201a) in treating patients with osteosarcoma, Wilms tumor (WT) or desmoplastic small round cell tumor (DSRCT) that is newly diagnosed or has come back after a period…
This randomized phase II trial studies paclitaxel, carboplatin, and bevacizumab or paclitaxel, carboplatin, and temsirolimus or ixabepilone, carboplatin, and bevacizumab to see how well they work in treating patients with stage III, stage…
The purpose of this study is to identify the recommended Phase 2 combination dose (RP2CD\[s\]) of the amivantamab and capmatinib combination therapy in participants with non-small cell lung cancer (NSCLC) in Phase 1 (combination dose…
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Rounds, approvals, launches and company moves from 13 trade and business feeds. Specialist bioscience outlets pass through. General business feeds have to earn their place on a keyword in the headline.
Manipal Health Enterprises’ $960.4 million initial public offering was oversubscribed on the final day of bidding on Friday, led by institutional investors, while valuation worries kept retail investors cautious. The…
TPG Capital and Permira are leading contenders for a significant minority stake in Cloudnine. The deal is expected to value India's largest maternity and pediatric hospital chain at approximately ₹11,000 crore. Binding…
Resilience and Lilly have invested $750m to boost production of Lilly’s KwikPen to boost the US supply of diabetes and obesity medicines.
Arboreal Bioinnovations, India’s first specialty food and nutraceutical ingredients technology company, today announced the successful close of its ₹230 crore Series A funding round. EAAA, the alternatives arm of…
The fresh capital will be used to scale the commercial deployment of Bumblebee, SUIND’s DGCA type-certified autonomous spraying UAS, accelerate the development of Wasp, its aerial intelligence and inspection UAS
Union Health Minister JP Nadda chaired a high-level meeting on August 1 to weigh expanding Project SARATHI, a volunteer-led patient assistance programme piloted at PGIMER Chandigarh, across Central Government hospitals…
The assessment and management of health workforce requirements is an ongoing and dynamic process carried out in coordination with State Governments and Union Territories based on evolving public health needs. To…
The Supreme Court Division Bench of Justice Vikram Nath and Justice Sandeep Mehta directed the Chief Secretaries and Health Secretaries of all States and Union Territories, as well as the National Commission for Allied…
Tata Trusts Chairman Noel Tata outlined a long-term vision for the Trusts, saying the organisation will focus on building institutions that strengthen India’s healthcare and education sectors while ensuring philanthropy…
The Government of India has appointed Air Marshal Sandeep Thareja, SM, VSM & Bar, as the next Director General Armed Forces Medical Services (DGAFMS), marking the culmination of an illustrious career spanning nearly four…
Vadodara-based Mediyant Technologies has secured regulatory approvals for the country’s first locally manufactured heart-lung machine with both USFDA 510(k) clearance and a CDSCO Class C manufacturing licence. The…
The global advanced endoscopic technologies market is poised for robust growth as healthcare providers increasingly adopt minimally invasive diagnostic and therapeutic procedures supported by high-definition imaging,…
Government of India has expanded biotechnology and Artificial Intelligence (AI)-enabled research in computational biology, bioinformatics, genomics, healthcare, medical imaging, biomanufacturing, biological data science…
The Government has been actively supporting Research, Development and Innovation through various schemes and initiatives that align with national priorities. The major Research & Development (R&D) initiatives taken by…
Responding to a question in the Rajya Sabha, the Union health ministry attributed the decline in India's exclusive breastfeeding rate to multiple factors, including socio-cultural practices, family customs, individual…
Leukaemia accounts for about 30% to 40% of all childhood cancer cases across Indian cancer registries. Acute Lymphoblastic Leukaemia (ALL) makes up 70% to 75% of all childhood leukaemia cases in the country.
The study led by doctors from Indira Gandhi Govt Medical College (IGGMC), Nagpur, has found that 53.3% of anti-TB prescriptions issued in healthcare settings outside National Tuberculosis Elimination Programme (NTEP) do…
The Ebola outbreak in the Democratic Republic of Congo is intensifying at an "exceptional" pace, the World Health Organization warned on Saturday, calling for a significant scaling-up of the health response. A vaccine…
Fertiliser sales touch 41.09 lt by July 17, against an estimated demand of 74.28 lt for the entire month
Turning crop residue from a seasonal pollution crisis into a reliable clean energy feedstock could reshape rural incomes, energy security, and India’s climate commitments, if policy and infrastructure catch up with the…
The next phase of Indian agriculture should help India nourish itself and biofortified crops offer us an opportunity
A 2025 study published in PubMed Central (PMC), titled Prevalence and Predictors of Hair Shedding Among GLP-1 Receptor Agonist Users, found that nearly seven out of ten GLP-1 users reported some degree of hair shedding…
In this photo essay, we showcase the YPS photography exhibition at Karnataka Chitrakala Parishath, along with curator insights.
The regulator said the actions were taken to protect consumers and ensure compliance with food safety laws. It warned that violations of the Food Safety and Standards Act, 2006, would invite strict legal and penal…
India's Foremost Pharma & Biotech Magazine ~ Power, Politics And Pharma The post Express Pharma August 2026 appeared first on Express Pharma .
Apnimed has raised $192 million for its upsized IPO, with the proceeds earmarked to fund the launch of its sleep apnea pill.
GSK is boosting its AI chops with a new deal worth up to $110 million with Relation.
Johnson & Johnson is cruising deeper into in vivo CAR-T waters, paying $785 million upfront to strike a deal that gives it the option to acquire Sail Biomedicines.<br>
Caldera Therapeutics has struck a reverse merger with the publicly traded Synlogic and inked a $278 million financing deal, continuing the meteoric rise of the inflammatory bowel disease startup.
A phase 3 trial of Novo Nordisk’s ziltivekimab has missed its primary endpoint, denting the prospects of a molecule analysts tipped to generate blockbuster sales and diversify the company’s portfolio. Novo has chances to…
Legend Biotech CEO Ying Huang, Ph.D., has left the company suddenly, without a predecessor in place. Huang was elevated from CFO to CEO in 2020 after a Chinese customs investigation was opened on founding CEO Fangliang…
Whether it's looming tariff threats or the rise of China, you need a truly global view to navigate today's biopharma industry.
Following a pair of FDA rejections of its melanoma drug, Replimune’s fortunes flipped today after an advisory committee voted 10 to 3 in favor of the candidate’s effectiveness.
BMS may have been absent from the dealmaking spree of some of its Big Pharma peers this year, but that might not change anytime soon.
Investors awaiting Bristol Myers Squibb’s key Alzheimer’s psychosis readout for Cobenfy and atrial fibrillation data for milvexian will have to wait a little longer.<br> <br>
Boston Scientific is cutting its financial guidance for the second quarter in a row as it gears up for a tough six months ahead.
Takeda has dropped another celiac disease therapy from its phase 2 pipeline, leaving the company with just one shot at treating the condition.
Attovia Therapeutics, Braveheart Bio and Vogenx have set target ranges for their IPOs, positioning the trio to collectively net more than $500 million from public investors. <br>
Labcorp continues to power along as it posts strong quarterly earnings led by growth in its diagnostics and lab services and triggering the medtech to raise its full-year guidance.<br>
Sanofi's new CEO Belén Garijo opened up for the first time about her strategy to reverse a trend of clinical setbacks, including dumping Regeneron-partnered IL-33 candidate itepekimab.
A panel of experts today voted against Capricor’s cell therapy for Duchenne muscular dystrophy, capping off an advisory committee meeting marked by statistical confusion.
After keeping tight-lipped for nearly two years, Merck & Co. briefly dropped the first concrete hint as to where it intends to take its PD-1xVEGF bispecific antibody—before quietly scrubbing the evidence.
Flush with GLP-1 cash and pipeline success, Eli Lilly rose from 16th to first over five years in Norstella’s inaugural Pipeline-to-Patient Productivity Index, which evaluated 25 large, global biopharma companies on…
A standard chemotherapy drug loaded in nanoparticles has been able to penetrate the blood-brain barrier when administered shortly after resection of the tumor, new research has suggested.
Biogen's business development team may have been busy in recent years, but CEO Christopher Viehbacher is easing off the acquisitions for a while.
Novo Nordisk’s attempt to dismiss a lawsuit about its CagriSema readout has failed, with the judge ruling that parts of the investors’ argument were strong enough for the case to proceed.
Processa Pharmaceuticals has made a push into the autoimmune space via the acquisition of Vidya Therapeutics, which delivers a potential rival to Novartis’ Rhapsido.
AbCellera’s T-cell engager platform has reeled in a second client this summer, with Vertex paying $28 million upfront for a collaboration that will include autoimmune conditions.
Incyte has ditched a JAK2 inhibitor in phase 1 development for a rare blood cancer in favor of “next-generation” replacements.
An experimental drug targeting both GLP-1 and glucagon receptors has curbed heavy drinking in a phase 2 trial, providing hope that the ubiquitous weight loss meds can be effectively harnessed against alcohol use disorder…
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